On-line Total Organic Carbon Analyzer

TOC-700S-OL

The TOC-700S-OL online total organic carbon analyzer is an instrument for determining the concentration of total organic carbon in water samples. It can detect TOC concentrations ranging from 0.001 mg/L to 100.0 mg/L, featuring high sensitivity, accuracy, and good stability.

The TOC-700S-OL is an online monitoring instrument with a compact design. Main components are installed on the main unit. Before measurement, the instrument requires gas line connection and reagent preparation. The instrument is controlled by dedicated software installed on the built-in display, enabling measurement, calibration, printing, and other data processing tasks.

Key Features

Online, UV/persulfate-NDIR, 0.001-100mg/L

10.4" Windows & audit trail, GMP/21 CFR 11

4 modes, gold NDIR, precise pump, dual condensate

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Brand: LabNav
Commodity name: On-line Total Organic Carbon Analyzer
Commodity ID: TOC-700S-OL
产品卖点1: Online, UV/persulfate-NDIR, 0.001-100mg/L
产品卖点2: 10.4" Windows & audit trail, GMP/21 CFR 11
产品卖点3: 4 modes, gold NDIR, precise pump, dual condensate

Product Details

Working Principle

UV/persulfate oxidation – NDIR detection principle. One sample is fully oxidized to CO₂ by UV and persulfate. Another sample has its inorganic carbon decomposed into CO₂ by acid reagent. CO₂, carried by carrier gas, passes through drying and impurity removal before entering a non-dispersive infrared (NDIR) detector for determination of carbon concentration in the sample.

Measurement Modes

Mode	Operating Principle
TC mode	Determines total carbon in the sample. The sample in the UV reactor is decomposed into CO₂ under the action of oxidant, acid reagent, and UV.
TIC mode	Determines inorganic carbon (carbonate and bicarbonate) in the sample. In the UV reactor, carbonate and bicarbonate are decomposed into CO₂ by acid reagent.
TOC mode	Determines organic carbon in the sample. TOC is measured by difference: TOC = TC – TIC. The sample sequentially measures TC and TIC; The TOC obtained by difference includes both volatile and nonvolatile organic carbon.
NPOC mode	Determines non-purgeable organic carbon in the sample. In the UV reactor, inorganic carbon is decomposed by acid reagent to CO₂ and purged, while volatile organic compounds are also purged. The remaining organic carbon is then decomposed into CO₂ by oxidants, acid reagents, and UV.

Patents

ZL 2014 2 0386326.8—A conductivity electrode with adjustable cell constant
ZL 2014 2 0386169.0—A device for detecting total organic carbon in ultra-pure water

Standards

USP <643> Total Organic Carbon (TOC) method
Chinese Pharmacopoeia 2020, Vol. IV, 0682 – Determination of total organic carbon in water for injection
GMP Annex – Computerized System Validation
21 CFR PART 11

Applications

Deionized water samples such as water for injection and purified water
Pharmaceutical industry cleaning validation
Environmental water, such as tap water, surface water
Chemical process water (cleaning water, cooling water, recycled water, etc.)
Laboratory research

Software Description

The software meets GMP computerized system validation requirements:
Electronic Signature
Login via username and password, each unique.
Password length requirements enhance security.
The manual screen lock function ensures operational uniqueness and safety.
Access Control
Multi-level permission settings.
Administrators can assign different permissions to operators, ensuring personnel only have privileges commensurate with their job functions.
Data Integrity
The audit trail function is enabled and cannot be turned off.
All test results are saved and cannot be modified or deleted.
All operations (any user entry) are recorded.
If a test method is modified, the changed parameters are recorded.
Data can be exported and backed up to protect stored data for future retrieval.

Features

Complies with EP, USP, and 2020 Chinese Pharmacopoeia requirements;
Four detection modes: TC, TIC, TOC, NPOC, all in the same reactor.
High reflectivity gold-plated gas cell, a high-concentration infrared light source, and a high-sensitivity infrared detector ensure excellent NDIR performance and sufficient sensitivity and accuracy for ppb-level measurements.
Precision electromagnetic metering pump ensures accuracy and stability of sample injection volume.
Dual-tube electronic condensation dehydration technology;
Real-time visible detection curve for better visualization;
Multiple real-time self-monitoring functions for temperature, pressure, and flow rate;
User definable calibration curve based on range, suitable for any water sample measurement;
Optional online module for continuous monitoring;
Optional autosampler for unattended operation, saving labor and time.

Specifications

Analysis Method	UV/persulfate oxidation – NDIR detection principle
TOC Detection Range	0.001 mg/L – 100.0 mg/L
Carrier Gas	High-purity nitrogen (CO₂-free air)
Oxidant	Sodium persulfate solution
Analysis Time	3–8 min
Accuracy Error	±5%
Repeatability Error	≤3 %
Ambient Temperature	0–40 ℃
Relative Humidity	≤ 85%
Detectable Items	TC, IC, TOC, NPOC
Injection Volume	50–6000 μL
Sample Temperature	0–100 °C
Acid Reagent	Phosphoric acid solution
TOC Detection Precision	0.001 mg/L
Zero Drift	±2 %/D
Span Drift	±2 %/D
Power Supply	220 ± 22 V AC, 50 ± 1 Hz
Power Consumption	150 W
Dimensions (W×D×H)	42 cm × 36.5 cm × 38 cm
Weight	21 kg